✕ Toxic

Yellow Oleander

Thevetia peruviana

Yellow Oleander (Thevetia peruviana) is an extremely dangerous and highly toxic plant for cats. All parts of the plant, including the leaves, flowers, and stems, contain deadly toxins. The seeds are especially potent and contain the highest concentration of these poisonous compounds. The toxins in Yellow Oleander are cardiac glycosides, specifically thevetin A and thevetin B. These chemicals directly attack the heart muscle, disrupting its ability to pump blood normally. They interfere with the heart's electrical signals, which can lead to a dangerously slow or fast heart rate, or other severe heartbeat irregularities known as arrhythmias. Even a very small amount, such as chewing on a leaf or seed, can be fatal. Any cat suspected of ingesting any part of a Yellow Oleander needs immediate, emergency veterinary care. Signs of poisoning include severe vomiting, diarrhea, drooling, weakness, tremors, and collapse. The effects on the heart are life-threatening and require urgent medical intervention. This is a true medical emergency.

Important Notes

Toxic compounds: thevetin A and thevetin B (cardiac glycosides) in all parts; seeds most concentrated

Mechanism: thevetins inhibit Na+/K+-ATPase in cardiac muscle, disrupting electrical conduction causing arrhythmias and heart block

Symptoms: vomiting, diarrhea, drooling, severe weakness, bradycardia, cardiac arrhythmias, hypotension, collapse; often fatal without treatment

Yellow Oleander seeds are particularly accessible when the fruit falls; the decorative yellow flowers are also attractive

Any suspected ingestion is a veterinary emergency

Potentially Toxic Parts

Stem

Bark

Seed

Entire Plant

Leaf

Flower

Fruit

Root

Sap

Possible Symptoms Reported in Cats

Bradycardia (abnormally slow heart rate) or tachycardia (rapid heart rate), and severe arrhythmias

Cardiac · Expected within the first 2 hours after exposure

Hyperkalemia (elevated potassium levels in the blood)

Hematological · Within the first 2 hours after exposure

Vomiting, diarrhea, excessive drooling, and abdominal pain

Gastrointestinal · Within the first 2 hours after exposure

Weakness and lethargy

Neurological · Within the first 2 hours after exposure

Tremors and seizures

Gastrointestinal · Often within the first few hours, progressing as the toxicosis worsens

Respiratory changes and difficulty breathing

Respiratory · Usually presents as the toxicity progresses (within hours)

Disclaimer: This summary was compiled from multiple sources and is for informational use only. It is not a diagnosis or treatment plan. Toxicity can vary based on the substance, amount, plant part, and individual cat. If you think your cat may have been exposed to a toxic substance, contact a veterinarian right away.