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Japanese Pieris
Pieris japonica
Japanese Pieris (Pieris japonica), also called lily-of-the-valley shrub or andromeda, is a highly toxic ornamental shrub. It is related to azalea and rhododendron, which are also dangerous for cats. The plant contains grayanotoxins in the leaves, flowers, stems, and nectar. These toxins interfere with normal nerve and muscle signals. They can affect the digestive system, heart, and brain, even when a cat eats only a small amount. Signs may include drooling, vomiting, diarrhea, weakness, slow or irregular heartbeat, tremors, seizures, or collapse. This is an emergency exposure. Keep Japanese Pieris away from cats, and contact a veterinarian or emergency clinic immediately if your cat eats any part of it.
Important Notes
Toxic compounds: grayanotoxins I, II, and III (diterpenoid polyols); all parts toxic including nectar
Mechanism: grayanotoxins bind to voltage-gated sodium channels, keeping them open; this causes persistent depolarisation of cardiac and skeletal muscle, leading to hypotension, bradycardia, and arrhythmias
Symptoms: profuse drooling, vomiting, diarrhea, severe weakness, loss of coordination, abnormally slow heart rate, low blood pressure, tremors, seizures; can be fatal
Even small ingestions can cause serious cardiac effects in cats
Any suspected ingestion is a veterinary emergency requiring immediate care
Potentially Toxic Parts
Stem
Leaf
Entire Plant
Flower
Possible Symptoms Reported in Cats
Weakness, Tremors, Seizures (Convulsions), Ataxia (loss of coordination), Depression, and Coma
Neurological · 1–4 hours.
Vomiting, Diarrhea, Hypersalivation (Drooling), and Anorexia (Refusal to eat)
Gastrointestinal · 1–4 hours (occasionally up to 12 hours).
Cardiac Arrhythmias, Bradycardia (slow heart rate), Tachycardia (fast heart rate), and Hypotension (low blood pressure)
Cardiac · 1–4 hours.
Dyspnea (Difficulty breathing)
Respiratory · 1–4 hours.
Transient Blindness / Blurred Vision
Neurological · 1–4 hours.
Disclaimer: This summary was compiled from multiple sources and is for informational use only. It is not a diagnosis or treatment plan. Toxicity can vary based on the substance, amount, plant part, and individual cat. If you think your cat may have been exposed to a toxic substance, contact a veterinarian right away.